Left ventricular assist pump pocket infection: conservative treatment strategy for destination therapy candidates
Int J Artif Organs 2017; 40(3): 90 - 95
Article Type: REVIEW
AuthorsElie Haddad, François-Xavier Lescure, Walid Ghodhbane, Laurent Lepage, Camille D’Humieres, William Vindrios, Yazdan Yazdanpanah, Patrick Nataf, Matthias Kirsch
Heart failure is a major cause of mortality and morbidity, particularly among patients with advanced disease and no access to cardiac transplantation. LVAD implantation is not only a bridge-to-transplantation option for patients awaiting a heart donor, but is often used as bridge-to-destination therapy in patients unsuited for transplantation for various reasons. LVAD infection is considered the second-most common cause of death in patients who survive the initial 6 months on LVAD support. Few reports describe the indications for chronic suppressing antibiotic therapy, device exchange, methods for exchanging infected devices, post-exchange antimicrobial management status, and the outcomes of such patients.
This is the case of a 74-year-old male patient with numerous comorbidities who received urgent surgical management for severe heart failure with a HeartMate II. Six months later he developed an LVAD pump infection with methicillin-resistant
We concisely reviewed the driveline infections and the main aspects of the LVAD pump infection. We reviewed options for conservative and nonconservative management and showed that conservative management of the LVAD pump infection is possible.
There are no defined recommendations for the management of LVAD pump infection. This case is among the few in the literature showing that conservative treatment of an LVAD pump infection is possible.
- • Accepted on 23/02/2017
- • Available online on 18/04/2017
- • Published in print on 21/04/2017
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- Haddad, Elie [PubMed] [Google Scholar] 1, 2, 3, * Corresponding Author (firstname.lastname@example.org)
- Lescure, François-Xavier [PubMed] [Google Scholar] 3
- Ghodhbane, Walid [PubMed] [Google Scholar] 4
- Lepage, Laurent [PubMed] [Google Scholar] 5
- D’Humieres, Camille [PubMed] [Google Scholar] 6
- Vindrios, William [PubMed] [Google Scholar] 3
- Yazdanpanah, Yazdan [PubMed] [Google Scholar] 3
- Nataf, Patrick [PubMed] [Google Scholar] 4
- Kirsch, Matthias [PubMed] [Google Scholar] 7
Department of Infectious Diseases, Faculty of Medicine, Saint-Joseph University, Hotel Dieu de France Hospital, Medical Sciences and Nursing Campus, Beirut - Lebanon
Department of Infectious Diseases, Pitié-Salpêtrière Hospital, Paris - France
Department of Infectious Diseases, Bichat Hospital, Paris - France
Department of Cardiac Surgery, Bichat Hospital, Paris - France
Department of Cardiology, Bichat Hospital, Paris - France
Laboratory of Microbiology, Bichat Hospital, Paris - France
Department of Cardiac Surgery, Lausanne University Hospital, Lausanne - Switzerland