Phosphate equilibration rate and daily clearance in patients on CAPD, CCPD and APD
Int J Artif Organs 2016; 39(12): 596 - 602
Article Type: ORIGINAL RESEARCH ARTICLE
AuthorsRafael Gomez, Jacek Waniewski, Adelaida Zapata, Mauro Pietribiasi, Bengt Lindholm
Criteria for how to assess removal rate of inorganic phosphorous (iP) in peritoneal dialysis (PD) and whether iP removal differs between different PD modalities are debated.
In a cross-sectional study, 73 prevalent patients on continuous ambulatory PD (n = 16), continuous cyclic PD (n = 8) or automated PD (n = 49) with mean age 54 (range, 18-87) years, 46 males, underwent standard peritoneal equilibration test (PET) and 24-hour collection of dialysate with measurements of iP, urea and creatinine in all samples and bags. There were 11 slow, 53 average, and 9 fast transporters.
D/P ratios for iP and creatinine at 4 h of PET were strongly correlated (
Creatinine is a good surrogate marker for phosphate removal, both as assessed by PET and by 24 hours’ clearance, in different PD modalities. Therefore, a separate PET scale for phosphate may not be needed. iP removal was greater with CAPD than APD but serum phosphate levels did not differ.
- • Accepted on 09/01/2017
- • Available online on 24/01/2017
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- Gomez, Rafael [PubMed] [Google Scholar] 1
- Waniewski, Jacek [PubMed] [Google Scholar] 2
- Zapata, Adelaida [PubMed] [Google Scholar] 1
- Pietribiasi, Mauro [PubMed] [Google Scholar] 2
- Lindholm, Bengt [PubMed] [Google Scholar] 3, * Corresponding Author (Bengt.Lindholm@ki.se)
Renal Unit, RTS Versalles, Cali - Colombia
Institute of Biocybernetics and Biomedical Engineering, Warsaw - Poland
Baxter Novum and Renal Medicine, Karolinska Institutet, Stockholm - Sweden