We present the test bench results of a valveless total artificial heart that is potentially compatible with the pediatric population.
The RollingHeart is a valveless volumetric pump generating pulsatile flow. It consists of a single spherical cavity divided into 4 chambers by 2 rotating disks. The combined rotations of both disks produce changes in the volumes of the 4 cavities (suction and ejection). The blood enters/exits the spherical cavity through 4 openings that are symmetrical to the fixed rotation axis of the first disk.
Mock circulatory system: The device pumps a 37% glycerin solution through 2 parallel circuits, simulating the pulmonary and systemic circulations. Flow rates are acquired with a magnetic inductive flowmeter, while pressure sensors collect pressure in the left and right outflow and inflow tracts.
In vitro test protocol: The pump is run at speeds ranging from 20 to 180 ejections per minute. The waveform of the pressure generated at the inflow and outflow of the 4 chambers and the flow rate in the systemic circulation are measured.
At an ejection rate of 178 min-1, the RollingHeart pumps 5.3 L/min for a systemic maximal pressure gradient of 174 mmHg and a pulmonary maximal pressure gradient of 75 mmHg. The power input was 14 W, corresponding to an efficiency of 21%.
The RollingHeart represents a new approach in the domain of total artificial heart. This preliminary study endorses the feasibility of a single valveless device acting as a total artificial heart.
Int J Artif Organs 2017; 40(12): 683 - 689
Article Type: ORIGINAL RESEARCH ARTICLE
AuthorsPiergiorgio Tozzi, Audrey Maertens, Jonathan Emery, Samuel Joseph, Matthias Kirsch, François Avellan
- • Accepted on 03/07/2017
- • Available online on 11/08/2017
- • Published in print on 24/11/2017
This article is available as full text PDF.
- Tozzi, Piergiorgio [PubMed] [Google Scholar] 1, * Corresponding Author (Piergiorgio.Tozzi@chuv.ch)
- Maertens, Audrey [PubMed] [Google Scholar] 2
- Emery, Jonathan [PubMed] [Google Scholar] 3
- Joseph, Samuel [PubMed] [Google Scholar] 3
- Kirsch, Matthias [PubMed] [Google Scholar] 1
- Avellan, François [PubMed] [Google Scholar] 2
Cardiovascular Surgery, Centre Hospitalier Universitaire Vaudois, Lausanne - Switzerland
Laboratory for Hydraulic Machines, EPFL, Ecole Polytechnique Fédérale Lausanne, Lausanne - Switzerland
Lausanne University School of Medicine, Lausanne - Switzerland