Abstract
To evaluate the need for prophylactic antibiotics in automated peritoneal dialysis (APD) patients undergoing flexible colonoscopy.
A total of 93 patients on automated peritoneal dialysis (APD) undergoing diagnostic colonoscopy were enrolled in a prospective, randomized study. Patients were randomized into 2 age- and sex-matched groups; group A (46 patients) with intraperitoneal (IP) ceftazidime prior to colonoscopy and group B (47 patients) without prophylactic antibiotics. The relations between peritonitis and different parameters were analyzed.
Of all colonoscopies, 60.2% showed normal findings, 17.2% with colonic polyps at different sites, 12.9% with angiodysplastic-like lesions, 5.4% with colonic ulcer(s), 3.2% with diverticulae without diverticulitis and 1.1% had transverse colon stricture. Post-colonoscopy peritonitis was documented in 3 (6.5%) and 4 (8.5%) patients in groups A and B, respectively (p = 0.2742); the causative organisms were mainly gram negative bacteria. Polypectomy was not associated with increased peritonitis episodes. By multiple logistic regression analysis, diabetes mellitus was the only independent variable that entered into the best predictive equation over the development of post-colonoscopy peritonitis but not antibiotic use.
The relation between prophylactic antibiotic use prior to colonoscopy in APD patients and the risk of peritonitis was lacking. Only diabetes mellitus appears to be of significance. Polypectomy did not increase peritonitis episodes.
Int J Artif Organs 2017; 40(10): 550 - 557
Article Type: ORIGINAL RESEARCH ARTICLE
DOI:10.5301/ijao.5000612
Authors
Abdullah K. Al-Hwiesh, Ibrahiem S. Abdul-Rahman, Mohammad A. Hussameldeen, Nadia Al-Audah, Abdalla Abdelrahman, Hala M. Moaigel, Tamer El-Salamony, Abdul-Salam Noor, Aisha Al-Osail, Dalal Al-Sayel, Nourah Al-DossariArticle History
- • Accepted on 23/05/2017
- • Available online on 05/07/2017
- • Published in print on 13/10/2017
Disclosures
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Authors
- Al-Hwiesh, Abdullah K. [PubMed] [Google Scholar] 1, * Corresponding Author ([email protected])
- Abdul-Rahman, Ibrahiem S. [PubMed] [Google Scholar] 1
- Hussameldeen, Mohammad A. [PubMed] [Google Scholar] 1
- Al-Audah, Nadia [PubMed] [Google Scholar] 1
- Abdelrahman, Abdalla [PubMed] [Google Scholar] 2
- Moaigel, Hala M. [PubMed] [Google Scholar] 1
- El-Salamony, Tamer [PubMed] [Google Scholar] 1
- Noor, Abdul-Salam [PubMed] [Google Scholar] 1
- Al-Osail, Aisha [PubMed] [Google Scholar] 1
- Al-Sayel, Dalal [PubMed] [Google Scholar] 1
- Al-Dossari, Nourah [PubMed] [Google Scholar] 1
Affiliations
-
Nephrology Division, Department of Internal Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam - Saudi Arabia -
Department of Electrical Engineering, Queens University, Kingston, Ontario - Canada
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